⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308709 | 0.71 | — | — | |
| SCHEMBL4472866 | 0.71 | — | — | |
| SCHEMBL14295009 | 0.71 | — | — | |
| SCHEMBL10265652 | 0.71 | — | — | |
| SCHEMBL10094142 | 0.71 | — | — | |
| SCHEMBL10094055 | 0.66 | — | — | |
| SCHEMBL13878998 | 0.66 | — | — | |
| SCHEMBL6827704 | 0.64 | — | — | |
| SCHEMBL243774 | 0.63 | ALDH1A1 (0.55) | — | |
| SCHEMBL9779717 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200885-A1 | PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | WO | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-107108554-B | 1-cyclohexyl-2-phenylaminobenzimidazole as MIDH1 inhibitor for treating tumors | 德国癌症研究中心 | 2020-11-06 | — | — | CN | disclosed |
| EP-3209660-B1 | 1-CYCLOHEXYL-2-PHENYLAMINOBENZIMIDAZOLES AS MIDH1 INHIBITORS FOR THE TREATMENT OF TUMORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3209660-B1 | 1-CYCLOHEXYL-2-PHENYLAMINOBENZIMIDAZOLES AS MIDH1 INHIBITORS FOR THE TREATMENT OF TUMORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS (DE) | 2020-06-17 | — | — | EP | disclosed |
| US-10137110-B2 | 1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-27 | — | — | US | disclosed |
| CN-108368143-A | Monomaleimide functionalized platinum compounds for cancer therapy | 维也纳医科大学 | 2018-08-03 | — | — | CN | disclosed |
| US-20170319549-A1 | 1-CYCLOHEXYL-2-PHENYLAMINOBENZIMIDAZOLES AS MIDH1 INHIBITORS FOR THE TREATMENT OF TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170319549-A1 | 1-CYCLOHEXYL-2-PHENYLAMINOBENZIMIDAZOLES AS MIDH1 INHIBITORS FOR THE TREATMENT OF TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170319549-A1 | 1-CYCLOHEXYL-2-PHENYLAMINOBENZIMIDAZOLES AS MIDH1 INHIBITORS FOR THE TREATMENT OF TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | US | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| US-4968594-A | PYRAZOLOTRIAZOLE-BASED MAGENTA COUPLER AND MEANS FOR FORMING UNSHARP POSITIVE IMAGE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0174873-B1 | SILVER HALIDE COLOR PHOTO-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1988-11-17 | — | — | EP | disclosed |
| EP-0236131-A2 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4690888-A | SLIGHTLY-DIFFUSABLE COLORED COMPOUNDS TO REACT WITH OXIDIZED DEVELOPERS; SHARPNESS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| EP-0174873-A2 | Silver halide color photo-sensitive material | KONICA CORPORATION (JP) | 1986-03-19 | — | — | EP | disclosed |