SCHEMBL5154968

SCHEMBL5154968

CCCC(OC(CCC)C(O)CO)C(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
TSHR P16473 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.35
CYP2D6 P10635 2/20 0.34
KDM4E B2RXH2 2/20 0.34
SPHK1 Q9NYA1 1/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CETP P11597 1/20 0.34
HTT P42858 1/20 0.34
UBE2N P61088 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27866619 0.84 LMNA (0.42) LMNATSHRSPHK1TDP1PTPN1
SCHEMBL2305353 0.84 LMNA (0.48) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL6689590 0.83 LMNA (0.43) LMNATSHRL3MBTL1CYP2D6KDM4E
SCHEMBL28508193 0.83 LMNA (0.38) LMNATSHRPTPN1
SCHEMBL1499941 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL2015033 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL940984 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL4105974 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL8502257 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN
SCHEMBL93582 0.82 CYP2D6 (0.52) LMNACYP2D6KDM4ESPHK1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040208783-A1 Process for the chemical and thermal disinfection AIR LIQUIDE SANTE (INTERNATIONAL ) (FR) 2004-10-21 US claimed
EP-1468606-A1 Process for the chemical and thermal disinfection Air Liquide Santé (International) (FR) 2004-10-20 EP claimed
US-5916884-A CYTOTOXIC THERAPEUTIC COMPOUND; ANTITUMOR AGENT MAX-PLANCK-GESELLSCHAFT ZUR FOEDERUNG DER WISSENSCHAFTEN (DE) 1999-06-29 US claimed
EP-0660696-B2 LIPSTICKS PROCTER & GAMBLE (US) 2007-01-10 EP disclosed
EP-1150645-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2005-08-24 EP disclosed
EP-0950392-B1 Non-sweating lipsticks PROCTER & GAMBLE (US) 2004-12-29 EP disclosed
EP-1152733-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2004-01-07 EP disclosed
EP-1152732-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2003-11-05 EP disclosed
US-6528071-B2 Containing vitamin B3 THE PROCTER & GAMBLE COMPANY 2003-03-04 US disclosed
US-6455055-B1 COSMETIC COMPOSITIONS INCLUDING LIPSTICKS, A CRYSTALLINE VITAMIN B.SUB.3 OR NIACIN, AN EMOLLIENT COMPONENT; , OF A SOLIDIFYING AGENT. THE COMPOSITIONS PROVIDE IMPROVED SKIN FEEL OF CRYSTALLINE VITAMIN B3 FOR SKIN THE PROCTER & GAMBLE COMPANY 2002-09-24 US disclosed
WO-2002036074-A2 PIGMENTED LIQUID CRYSTAL MATERIALS PRESPERSE INCORPORATED (US) 2002-05-10 WO disclosed
WO-2000047182-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2000-08-17 WO disclosed
WO-2000047171-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 THE PROCTER & GAMBLE COMPANY (US) 2000-08-17 WO disclosed
EP-0950392-A1 Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1999-10-20 EP disclosed
US-5843407-A Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1998-12-01 US disclosed
EP-0660696-B1 LIPSTICKS PROCTER & GAMBLE (US) 1997-01-08 EP disclosed
EP-0725620-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1996-08-14 EP disclosed
EP-0660696-A1 LIPSTICKS. PROCTER & GAMBLE (US) 1995-07-05 EP disclosed
WO-1995011000-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1995-04-27 WO disclosed
WO-1994006400-A1 LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1994-03-31 WO disclosed