SCHEMBL515497

SCHEMBL515497

CSCc1ccccc1SC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC6A2 P23975 4/20 0.39
SLC6A4 P31645 4/20 0.39
SLC6A3 Q01959 3/20 0.39
LMNA P02545 2/20 0.38
APOBEC3G Q9HC16 1/20 0.38
KDM4E B2RXH2 2/20 0.37
IDO1 P14902 1/20 0.36
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
POLB P06746 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CHRM4 P08173 1/20 0.34
HTR7 P34969 1/20 0.34
P2RX7 Q99572 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28762436 0.86 SLC6A4 (0.44) ALDH1A1SLC6A2SLC6A4SLC6A3LMNA
SCHEMBL515496 0.82 CHRM2 (0.46) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL3083039 0.82 MAPT (0.39) CHRM2MAPTSLC6A2SLC6A4SLC6A3
SCHEMBL20738393 0.79 CHRM2 (0.43) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL8481321 0.78 CHRM2 (0.50) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL13884146 0.77 CHRM2 (0.42) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL1146257 0.76 CHRM2 (0.48) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL7048508 0.76 CHRM2 (0.48) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL2169643 0.76 CHRM2 (0.48) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2
SCHEMBL1146142 0.76 APOBEC3G (0.67) CHRM2ALDH1A1MAPTL3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911974-B2 Metal/resin composite structure and method for manufacturing same DIC CORPORATION (JP) 2024-02-27 US disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-20230279228-A1 POLYARYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE, AND METHODS FOR PRODUCING THESE DIC CORPORATION (JP) 2023-09-07 US disclosed
US-11565480-B2 Metal-resin composite and method for producing same DIC CORPORATION (JP) 2023-01-31 US disclosed
US-20210347127-A1 METAL-RESIN COMPOSITE AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2021-11-11 US disclosed
US-10737427-B2 Long fiber-reinforced polyarylene sulfide resin molded article and method for producing the same DIC CORPORATION (JP) 2020-08-11 US disclosed
EP-3275620-B1 METHOD FOR PRODUCING A FIBRE-REINFORCED POLYARYLENE SULFIDE RESIN MOLDED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2019-11-13 EP disclosed
US-20180043602-A1 LONG FIBER-REINFORCED POLYARYLENE SULFIDE RESIN MOLDED ARTICLE AND METHOD FOR PRODUCING THE SAME DIC CORPORATION (JP) 2018-02-15 US disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 CHRM2 67/4885ALDH1A1 1574/4885MAPT 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.