Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.54 |
| ▸ | CTSK | P43235 | 11/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151231 | 0.90 | CTSS (0.53) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL5150943 | 0.90 | CTSS (0.53) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL23742817 | 0.88 | CTSS (0.56) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6952987 | 0.86 | CTSS (0.54) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL5155420 | 0.85 | CTSS (0.53) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL18920548 | 0.85 | CTSS (0.53) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL1350140 | 0.84 | PTPN1 (0.62) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL1350138 | 0.84 | PTPN1 (0.62) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL3450109 | 0.84 | PTPN1 (0.62) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL31524193 | 0.84 | CTSS (0.59) | CTSSCTSKCTSBCTSLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |