Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514911 | 0.93 | MAPT (0.54) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL515377 | 0.91 | MAPT (0.57) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL9425032 | 0.91 | MAPT (0.57) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL29078434 | 0.91 | MAPT (0.57) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL514942 | 0.91 | MAPT (0.57) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL515402 | 0.91 | TSHR (0.56) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL29482081 | 0.89 | TSHR (0.56) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL4441350 | 0.88 | MAPT (0.54) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11741456 | 0.87 | TSHR (0.60) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL514867 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344942-B | Compounds that modulate voltage-gated sodium channels | 会聚制药有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-116265466-A | Synthesis of compounds that modulate use-dependent voltage-gated sodium channels | 生物基因麻省公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-108430471-B | Factor XIa inhibitors | 默沙东公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-107344942-B | Compounds that modulate voltage-gated sodium channels | 会聚制药有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111526874-A | Process for the preparation of spiro derivatives | 生物基因公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-102369173-B | Method for producing high-purity terminal olefin compound | KURARAY CO | 2014-09-10 | — | — | CN | disclosed |
| WO-2014022752-A1 | MACROCYCLES AS PIM INHIBITORS | AMGEN INC. (US) | 2014-02-06 | — | — | WO | disclosed |
| EP-2415740-B1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-8609886-B2 | Method for producing high purity terminal olefin compound | KURARAY CO., LTD. (JP) | 2013-12-17 | — | — | US | disclosed |
| CN-102369173-A | Method for producing high-purity terminal olefin compound | KURARAY CO | 2012-03-07 | — | — | CN | disclosed |
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| EP-1734061-B1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS INC (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1734061-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20040122192-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20020156207-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1186619-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | Mitsui Chemicals, Inc. (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-5684208-A | HYDROFORMYLATION OF BUTADIENE, RHODIUM/PHOSPHINE COMPLEX CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| US-4039585-A | Hydroformylation process | UOP INC. (US) | 1977-08-02 | — | — | US | disclosed |