Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514536 | 0.93 | TSHR (0.56) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL29482081 | 0.93 | TSHR (0.56) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL515429 | 0.91 | TSHR (0.60) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL21494961 | 0.91 | TSHR (0.60) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL11741456 | 0.91 | TSHR (0.60) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL515048 | 0.91 | TSHR (0.60) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL514878 | 0.91 | TSHR (0.50) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL515561 | 0.91 | TSHR (0.50) | TSHRALDH1A1MAPTABCC4KMT2A | |
| SCHEMBL4441350 | 0.88 | MAPT (0.54) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL25340115 | 0.87 | TSHR (0.67) | TSHRALDH1A1MAPTABCC4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266503-B1 | Sulfoxide ligand metal catalyzed oxidation of olefins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-04-23 | — | — | US | disclosed |
| CN-102369173-B | Method for producing high-purity terminal olefin compound | KURARAY CO | 2014-09-10 | — | — | CN | disclosed |
| EP-2415740-B1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-8609886-B2 | Method for producing high purity terminal olefin compound | KURARAY CO., LTD. (JP) | 2013-12-17 | — | — | US | disclosed |
| CN-102369173-A | Method for producing high-purity terminal olefin compound | KURARAY CO | 2012-03-07 | — | — | CN | disclosed |
| EP-2415740-A1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | Kuraray Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029229-A1 | METHOD FOR PRODUCING HIGH PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| EP-1734061-B1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS INC (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1734061-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20040122192-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-6710074-B2 | FOR THERAPY OF MALARIA | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20030078291-A1 | Novel compound having antimalarial activity | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2003-04-24 | — | — | US | disclosed |
| US-20020156207-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1186619-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | Mitsui Chemicals, Inc. (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-3956316-A | PROGESTATIONAL AND SALT-RETAINING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078291-A1 | Novel compound having antimalarial activity | CYP51A1, CASP12, TBXAS1 | TSHR 3617/4885ALDH1A1 1554/4885MAPT 4479/4885 |
| US-20120029229-A1 | METHOD FOR PRODUCING HIGH PURITY TERMINAL OLEFIN COMPOUND | ADH1A, ADH1C, OSBP | TSHR 3218/4885ALDH1A1 233/4885MAPT 1768/4885 |
| US-10266503-B1 | Sulfoxide ligand metal catalyzed oxidation of olefins | YAP1, ICOSLG, SPIN3 | TSHR 1538/4885ALDH1A1 1012/4885MAPT 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.