SCHEMBL5155637

SCHEMBL5155637

CO[Si](CCCOc1cccc(N)c1)(OC)OC.C[Si](C)(C)CN

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CYP3A4 P08684 2/20 0.47
TP53 P04637 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAOB P27338 1/20 0.41
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
APP P05067 1/20 0.38
MAPK1 P28482 2/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109946 0.93 TSHR (0.59) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL30781624 0.93 TSHR (0.59) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL6567041 0.83 TSHR (0.49) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL961436 0.82 TSHR (0.58) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL8361890 0.82 TSHR (0.58) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL4436282 0.82 TSHR (0.49) TSHRCYP3A4TP53ALDH1A1MAPK1
SCHEMBL568194 0.78 TSHR (0.60) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL29981537 0.78 TSHR (0.60) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL893806 0.78 TSHR (0.59) TSHRCYP3A4TP53ALDH1A1MAOB
SCHEMBL10594544 0.75 TSHR (0.56) TSHRCYP3A4TP53ALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1782436-A2 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE Novinium, Inc. (US) 2007-05-09 EP disclosed
EP-1744866-A2 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES Novinium, Inc. (US) 2007-01-24 EP disclosed
WO-2005084321-A2 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2005-09-15 WO disclosed
WO-2005084322-A2 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES NOVINIUM, INC. (US) 2005-09-15 WO disclosed