Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isalmadol SCHEMBL5534029 | 0.90 | SLC6A2 (0.66) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| Isalmadol SCHEMBL6437705 | 0.90 | SLC6A2 (0.66) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| Isalmadol SCHEMBL29711375 | 0.90 | SLC6A2 (0.66) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL7019410 | 0.87 | SLC6A2 (0.62) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL5012494 | 0.87 | SLC6A2 (0.62) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL29966428 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL15654221 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL20473750 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL159543 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL14964805 | 0.85 | SLC6A2 (0.67) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742621-A2 | AGENT-RELEASING SYSTEM COMPRISING AN AGENT-CONTAINING PATCH AND AT LEAST ONE MEANS REGULATING THE RELEASE OF AGENTS | Grünenthal GmbH (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005102270-A2 | AGENT-RELEASING SYSTEM COMPRISING AN AGENT-CONTAINING PATCH AND AT LEAST ONE MEANS REGULATING THE RELEASE OF AGENTS | Grünenthal GmbH (DE) | 2005-11-03 | — | — | WO | disclosed |