SCHEMBL5156777

SCHEMBL5156777

NC(=O)/C=C\C(=O)N[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245241 0.74
SCHEMBL156118 0.74
SCHEMBL27641218 0.74 ALDH1A1 (0.50)
SCHEMBL156117 0.74
SCHEMBL28797787 0.74
SCHEMBL31277469 0.74
SCHEMBL11822127 0.74
SCHEMBL5175963 0.72
SCHEMBL9728297 0.72 MAPT (0.52)
SCHEMBL381340 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439182-B1 Imidosilane compositions GEN ELECTRIC (US) 2007-02-14 EP disclosed
EP-1439182-A1 Imidosilane compositions CROMPTON CORPORATION (US) 2004-07-21 EP disclosed
US-6191286-B1 REACTING AN AMINO ALKYL DIALKOXYSILANE OR AMINO TRAIALKOXYSILANE AND UNSATURATED ACID ANHYDRIDE TO FORM AN AMICACID SILANE, TREATING AMICACID SILANE WITH A SILYLATING OR ESTERIFYING CAPPING AGENT, HEATING TO FORM IMIDOSILANE OSI SPECIALTIES INC. 2001-02-20 US disclosed
EP-0982311-A2 Imidosilane compositions CK WITCO CORPORATION (US) 2000-03-01 EP disclosed