Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598461 | 0.86 | L3MBTL1 (0.64) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL29639741 | 0.86 | L3MBTL1 (0.64) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL5156921 | 0.75 | L3MBTL1 (0.60) | NPC1L3MBTL1HTTKMT2ALMNA | |
| SCHEMBL29738645 | 0.74 | NPC1 (0.64) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL878658 | 0.74 | NPC1 (0.64) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL13647205 | 0.73 | NPC1 (0.58) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| Benzene SCHEMBL28216480 | 0.73 | NPC1 (0.67) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| Isopropyl Alcohol SCHEMBL19136090 | 0.73 | HTT (0.68) | NPC1HPGDALDH1A1L3MBTL1HTT | |
| SCHEMBL2543077 | 0.73 | L3MBTL1 (0.56) | NPC1ALDH1A1L3MBTL1HTTKMT2A | |
| SCHEMBL21128714 | 0.72 | NPC1 (0.83) | NPC1HPGDALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747224-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | Universita' Degli Studi di Udine (IT) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005105819-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE (IT) | 2005-11-10 | — | — | WO | disclosed |