SCHEMBL5156946

SCHEMBL5156946

COc1cc(OC)cc(-[n+]2ccc(-c3cc[n+](C)cc3)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42
SLC6A4 P31645 1/20 0.42
CYP1A1 P04798 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2E1 P05181 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C8 P10632 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2A6 P11509 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP4B1 P13584 2/20 0.41
CYP2B6 P20813 2/20 0.41
CYP3A5 P20815 2/20 0.41
CYP2A7 P20853 2/20 0.41
CYP3A7 P24462 2/20 0.41
CYP2F1 P24903 2/20 0.41
CYP2C18 P33260 2/20 0.41
CYP2C19 P33261 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157414 0.83 SLC22A2 (0.43) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
SCHEMBL13943810 0.76 ACHE (0.55) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL16433677 0.75 SLC6A4 (0.56) SLC22A2SLC22A1SLC22A3SLC6A4QDPR
SCHEMBL29738939 0.75 SLC22A2 (0.46) SLC22A2SLC22A1SLC22A3SLC6A4QDPR
Iodide SCHEMBL31621361 0.74 ESR2 (0.52) SLC22A2SLC22A1SLC22A3SLC6A4QDPR
SCHEMBL17996980 0.74 CA1 (0.50) CYP3A4ALDH1A1ABL1ABCB1BCR
SCHEMBL29738922 0.73 SLC6A4 (0.45) SLC22A2SLC22A1SLC22A3SLC6A4QDPR
SCHEMBL29738945 0.70 SLC22A2 (0.42) SLC22A2SLC22A1SLC22A3SLC6A4QDPR
SCHEMBL10256951 0.70
SCHEMBL5159624 0.70 SLC22A2 (0.70) SLC22A2SLC22A1SLC22A3SLC6A4QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
CN-119504576-A Application of cathode material in reduction of oxidation-reduction potential and electrochromic device 宁波华瓴光学技术有限公司 2025-02-25 CN disclosed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 US disclosed
US-6661559-B2 Transparent substrate having an electrically conductive material; redox electroactive compounds; colorimetric analysis GENTEX CORPORATION 2003-12-09 US disclosed