SCHEMBL515719

SCHEMBL515719

CC(C)CC(N)C(=O)NC([C]=O)CS

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.41
LARS1 Q9P2J5 2/20 0.37
ENPEP Q07075 2/20 0.37
SCN9A Q15858 3/20 0.36
ANPEP P15144 3/20 0.36
RNPEP Q9H4A4 2/20 0.36
DNPEP Q9ULA0 1/20 0.36
AAK1 Q2M2I8 1/20 0.35
ERAP2 Q6P179 1/20 0.35
ERAP1 Q9NZ08 1/20 0.35
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515720 1.00 SLC7A5 (0.41) SLC7A5LARS1ENPEPSCN9AANPEP
SCHEMBL29010766 0.88 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL29010817 0.88 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL2193200 0.88 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL7318989 0.88 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL21625553 0.88 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL28057635 0.85 SLC7A5 (0.42) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL9797642 0.82 SLC7A5 (0.40) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL7557893 0.82 SLC7A5 (0.40) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL1795666 0.82 SLC7A5 (0.40) SLC7A5LARS1SCN9AANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692169-B2 Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells CELLECTIS (FR) 2023-07-04 US disclosed
US-20230192857-A1 INHIBITION OF CYTOKINE-INDUCED SH2 PROTEIN IN NK CELLS WALTER & ELIZA HALL INST MEDICAL RES (AU) 2023-06-22 US disclosed
US-20220178938-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS, INC. 2022-06-09 US disclosed
US-20220073931-A1 ANTISENSE OLIGONUCLEOIDES OF GLUTATHIONE S-TRANSFERASES FOR CANCER TREATMENT ATSO CORP AFFAIRS S A DE C V (MX) 2022-03-10 US disclosed
US-20200407682-A1 CELLS FOR IMMUNOTHERAPY ENGINEERED FOR TARGETING ANTIGEN PRESENT BOTH ON IMMUNE CELLS AND PATHOLOGICAL CELLS CELLECTIS (FR) 2020-12-31 US disclosed
US-20190317107-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS INC (US) 2019-10-17 US disclosed
US-20180172696-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS INC (US) 2018-06-21 US disclosed
US-20170166981-A1 BIOMARKERS AND METHODS OF USE THEREOF THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE 2017-06-15 US disclosed
US-20170146548-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS INC (US) 2017-05-25 US disclosed
US-9493522-B2 Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-15 US disclosed
EP-3004141-A1 HISTONE DEACETYLASE ( HDAC) BIOMARKERS IN MULTIPLE MYELOMA Acetylon Pharmaceuticals, Inc. (US) 2016-04-13 EP disclosed
EP-2972308-A2 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH Sera Prognostics, Inc. (US) 2016-01-20 EP disclosed
US-20150309047-A1 CIRCULATING PROTEOLYTIC BIOMARKERS OF CELL DEATH AND METHODS FOR THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-10-29 US disclosed
WO-2014197471-A1 HISTONE DEACETYLASE ( HDAC) BIOMARKERS IN MULTIPLE MYELOMA ACETYLON PHARMACEUTICALS, INC. (US) 2014-12-11 WO disclosed
US-20140287950-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS, INC. (US) 2014-09-25 US disclosed
US-20140287948-A1 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS, INC. (US) 2014-09-25 US disclosed
WO-2014144129-A2 BIOMARKERS AND METHODS FOR PREDICTING PRETERM BIRTH SERA PROGNOSTICS, INC. (US) 2014-09-18 WO disclosed
US-20140024539-A1 BIOMARKERS AND METHODS OF USE THEREOF TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2014-01-23 US disclosed
US-20120028266-A1 DISCOVERY OF CANDIDATE BIOMARKERS OF IN VIVO APOPTOSIS BY GLOBAL PROFILING OF CASPASE CLEAVAGE SITES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-02-02 US disclosed
EP-0456758-A1 ANAPHYLATOXIN-RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 1991-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192857-A1 INHIBITION OF CYTOKINE-INDUCED SH2 PROTEIN IN NK CELLS IL2, ILF2, CD74 SLC7A5 3093/4885LARS1 3030/4885ENPEP 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.