Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC1A5 | Q15758 | 8/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157382 | 1.00 | LTA4H (0.54) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| Hydrochloric Acid SCHEMBL4847778 | 0.99 | LTA4H (0.53) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| Hydrochloric Acid SCHEMBL1023741 | 0.99 | LTA4H (0.53) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| SCHEMBL14002362 | 0.81 | MME (0.51) | MEN1KMT2AFFAR1 | |
| SCHEMBL14002414 | 0.81 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL14002366 | 0.81 | MME (0.51) | MEN1KMT2AFFAR1 | |
| SCHEMBL7369714 | 0.81 | LTA4H (0.51) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| SCHEMBL15957303 | 0.80 | LTA4H (0.57) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| SCHEMBL12954668 | 0.80 | PPARG (0.47) | MEN1KMT2APKM | |
| SCHEMBL20335142 | 0.79 | KMT2A (0.56) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515983-B1 | ANTIBACTERIAL AMIDE MACROCYCLES | AICURIS GMBH & CO KG (DE) | 2007-02-21 | — | — | EP | disclosed |
| EP-1526896-A1 | ANTIBACTERIAL ESTER MACROCYCLES | Bayer HealthCare AG (DE) | 2005-05-04 | — | — | EP | disclosed |
| EP-1515983-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | Bayer HealthCare AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004012816-A1 | ANTIBACTERIAL ESTER MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003106480-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2003-12-24 | — | — | WO | disclosed |