Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
| ▸ | DRD3 | P35462 | 3/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890259 | 0.84 | — | — | |
| SCHEMBL279674 | 0.82 | — | — | |
| SCHEMBL18415311 | 0.79 | NTRK1 (0.38) | NTRK1NPC1RAB9AGRM5IRAK4 | |
| SCHEMBL2823462 | 0.76 | KDM4E (0.47) | NPC1 | |
| SCHEMBL20181862 | 0.67 | KMT2A (0.50) | NPC1RAB9A | |
| SCHEMBL19578089 | 0.67 | — | — | |
| SCHEMBL12060188 | 0.67 | — | — | |
| SCHEMBL10021906 | 0.66 | SMPD3 (0.48) | SMPD3HDAC4HRH1HRH4 | |
| SCHEMBL15277189 | 0.65 | SMPD3 (0.31) | SMPD3 | |
| SCHEMBL19505626 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988290-B1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| US-6410744-B1 | REACTING AN IMIDAZOLE COMPOUND WITH PHOSGENE IN A SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-0988290-A1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056769-A1 | CARBONYLDIIMIDAZOLES, THEIR ESTER DERIVATIVES AND METHOD FOR THEIR PRODUCTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | disclosed |