⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701424 | 0.86 | HCAR3 (0.33) | — | |
| SCHEMBL5157429 | 0.84 | SMPD3 (0.34) | — | |
| SCHEMBL279674 | 0.80 | — | — | |
| SCHEMBL31118042 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL18415311 | 0.77 | NTRK1 (0.38) | — | |
| SCHEMBL8306045 | 0.74 | PIN1 (0.52) | — | |
| SCHEMBL5651735 | 0.73 | — | — | |
| SCHEMBL5650390 | 0.73 | — | — | |
| SCHEMBL2823331 | 0.72 | HCAR2 (0.43) | — | |
| SCHEMBL30889539 | 0.72 | HCAR3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132111-A1 | Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics | PROSETTA BIOSCIENCES INC (US) | 2026-05-14 | — | — | US | disclosed |
| US-12459901-B2 | Host-targeted pan-respiratory antiviral small molecule therapeutics | PROSETTA BIOSCIENCES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4402124-A1 | NOVEL HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS | Prosetta Biosciences, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| US-12017997-B2 | Host-targeted pan-respiratory antiviral small molecule therapeutics | PROSETTA BIOSCIENCES, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240190826-A1 | Novel Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics | PROSETTA BIOSCIENCES, INC. | 2024-06-13 | — | — | US | disclosed |
| WO-2024076155-A1 | NOVEL COMPOUND AS YEATS DOMAIN INHIBITOR | 노보렉스 주식회사 | 2024-04-11 | — | — | WO | disclosed |
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| US-20230147603-A1 | HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS | PROSETTA BIOSCIENCES, INC. | 2023-05-11 | — | — | US | disclosed |
| WO-2023069770-A1 | NOVEL HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS | PROSETTA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114230522-A | Imidazole-2-carboxylic acid metal beta-lactamase inhibitor and preparation method and application thereof | 四川大学 | 2022-03-25 | — | — | CN | disclosed |
| US-8461160-B2 | Dihydropyrimidinones | HOFFMANN-LA ROCHE, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100286158-A1 | DIHYDROPYRIMIDINONES | HOFFMANN-LA ROCHE, INC. | 2010-11-11 | — | — | US | disclosed |
| US-4588817-A | Antibiotic nodusmicins | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4461903-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| US-4448970-A | ANTIBIOTICS, BACTERICIDES | THE UPJOHN COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4363922-A | Esters of antibiotic nodusmicin | THE UPJOHN COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4360683-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4351769-A | Antibiotic composition of matter | THE UPJOHN COMPANY (US) | 1982-09-28 | — | — | US | disclosed |