SCHEMBL515747

SCHEMBL515747

COCCC(=O)c1ccc(OC)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.77
PDE4B Q07343 1/20 0.64
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
MMP1 P03956 1/20 0.62
HDAC1 Q13547 5/20 0.61
HDAC8 Q9BY41 5/20 0.61
HDAC3 O15379 3/20 0.61
HDAC4 P56524 3/20 0.61
HDAC7 Q8WUI4 3/20 0.61
HDAC2 Q92769 3/20 0.61
HDAC10 Q969S8 3/20 0.61
HDAC11 Q96DB2 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61
HDAC9 Q9UKV0 3/20 0.61
HDAC5 Q9UQL6 3/20 0.61
GSK3B P49841 1/20 0.61
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CES2 O00748 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30552434 0.89 PDE4B (0.70) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL16552644 0.88 MMP1 (0.76) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL4082864 0.84 PDE4B (0.86) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL3171960 0.84 PDE4B (0.79) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL20135180 0.82 KMT2A (0.60) MAPTNPC1RAB9AHDAC1HDAC6
SCHEMBL2633872 0.82 MAPT (0.68) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL28394787 0.82 HSD17B3 (0.62) MAPTNPC1RAB9ACA1CA2
SCHEMBL705208 0.82 MAPT (0.68) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL16998568 0.82 MAPT (0.53) MAPTPDE4BNPC1RAB9AMMP1
SCHEMBL16563404 0.81 MAPT (0.53) MAPTPDE4BNPC1RAB9AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
CN-114751576-A Method for treating dialkoxybenzene production wastewater 北京惠宇乐邦环保科技有限公司 2022-07-15 CN claimed
CN-105494381-A Pesticide for prevention and control of callosobruchus maculatus YANTAI SHUNLONG CHEMICAL TECH CO LTD 2016-04-20 CN claimed
CN-103435507-B Preparation method of L-alpha-methyl-3,4-dihydroxyphenylalanine SHANDONG XINHUA PHARMACEUTICAL 2015-03-25 CN claimed
CN-103435507-A Preparation method of L-alpha-methyl-3,4-dihydroxyphenylalanine SHANDONG XINHUA PHARMACEUTICAL 2013-12-11 CN claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US disclosed
CN-118184502-A Method for preparing veratone 济南悟通生物科技有限公司 2024-06-14 CN disclosed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
WO-1987002661-A1 RACEMIC NORDIHYDROGUAIARETIC ACID AND INTERMEDIATES CHEMEX PHARMACEUTICALS, INC. (US) 1987-05-07 WO disclosed
EP-0217204-A1 Trans-2-(3,4,5-trimethoxyphenyl)-5-(5,6-dimethoxy-3-pyridyl)-tetrahydrothiophene, a PAF-antagonist MERCK & CO. INC. (US) 1987-04-08 EP disclosed
US-4562298-A Optically active nordihydroguaiaretic acid and intermediates CHEMEX PHARMACEUTICALS, INC. (US) 1985-12-31 US disclosed
EP-0154887-A1 New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists MERCK & CO. INC. (US) 1985-09-18 EP disclosed
US-4186129-A CENTRAL NERVOUS SYSTEM DEPRESSANTS, ANTICONVULSANTS SCHERING AKTIENGESELLSCHAFT (DE) 1980-01-29 US disclosed