SCHEMBL5157716

SCHEMBL5157716

CC(=O)NCCOCCNC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.55
KDM4E B2RXH2 2/20 0.55
HIF1A Q16665 1/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
MTNR1A P48039 5/20 0.50
MTNR1B P49286 5/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 3/20 0.48
USP2 O75604 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PAOX Q6QHF9 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ADRA1A P35348 1/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5155263 0.97 MEN1 (0.56) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL19309079 0.97 MEN1 (0.56) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL48874 0.91 MAPK1 (0.46) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL10046200 0.91 MAPK1 (0.46) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL1826677 0.91 EPHX2 (0.47) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL25377212 0.89 MAPK1 (0.44) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL22526372 0.89 MEN1 (0.48) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL21771222 0.89 MEN1 (0.48) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL24746941 0.89 MAPK1 (0.44) MAPK1KDM4EHIF1AMEN1KMT2A
SCHEMBL22906372 0.89 MEN1 (0.48) MAPK1KDM4EHIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762901-B9 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING CIS BIO INT (FR) 2007-01-17 EP claimed
EP-0762901-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING BERLEX INC (US) 2006-04-19 EP claimed
CN-1087630-C Radiolabeled compounds for imaging thrombi DIATECH INC (US) 2002-07-17 CN claimed
US-6074627-A STABLE COMPLEX DIATIDE, INC. (US) 2000-06-13 US claimed
US-5997844-A Technetium-99m labeled peptides for imaging DIATIDE, INC. (US) 1999-12-07 US claimed
US-5830856-A RADIOLABELED SCINTIGRAPHIC IMAGING DIATIDE, INC. (US) 1998-11-03 US claimed
CN-1154071-A Radiolabeled compounds for imaging thrombi DIATECH INC (US) 1997-07-09 CN claimed
EP-0772460-A1 RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING DIATECH, INC. (US) 1997-05-14 EP claimed
EP-0762901-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1997-03-19 EP claimed
WO-1995033496-A1 RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING DIATECH, INC. (US) 1995-12-14 WO claimed
WO-1995033498-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1995-12-14 WO claimed
WO-2023242597-A1 BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LIMITED (GB) 2023-12-21 WO disclosed
US-11809077-B2 Photoresist compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-11-07 US disclosed
US-11809077-B2 Photoresist compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-11-07 US disclosed
US-20220043342-A1 PHOTORESIST COMPOSITIONS AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-02-10 US disclosed
US-4329504-A COUPLERS FOR DYES, HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1982-05-11 US disclosed
US-4311478-A HAIR DYES L'OREAL (FR) 1982-01-19 US disclosed
US-4259261-A OXIDATION COLOR DYES FOR HAIR L'OREAL (FR) 1981-03-31 US disclosed
US-4152112-A Dyeing composition for keratinic fibers containing paraphenylenediamines L'OREAL (FR) 1979-05-01 US disclosed
US-3983138-A HYPOTENSIVES MERCK & CO., INC. (US) 1976-09-28 US disclosed