Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038326 | 0.98 | MEN1 (0.48) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL8400303 | 0.98 | MEN1 (0.48) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL22056507 | 0.91 | MAPK1 (0.43) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL5157716 | 0.91 | MAPK1 (0.55) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL19309079 | 0.88 | MEN1 (0.56) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL5155263 | 0.88 | MEN1 (0.56) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL22199409 | 0.87 | MEN1 (0.41) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL22199596 | 0.87 | MAPK1 (0.48) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL13056647 | 0.85 | MAPK1 (0.58) | MAPK1KDM4EHIF1ATSHRMEN1 | |
| SCHEMBL31430522 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319008-A1 | HAIR COMPOSITIONS USES AND METHODS THEREOF | FUNCTION INC (US) | 2025-10-16 | — | — | US | claimed |
| WO-2025137404-A1 | ODOR BINDING PROTEIN COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | K18, INC. (US) | 2025-06-26 | — | — | WO | claimed |
| US-20250000787-A1 | PROBIOTIC SKIN FORMULATIONS | CROWN LABORATORIES, INC. | 2025-01-02 | — | — | US | claimed |
| EP-4167937-A1 | PROBIOTIC SKIN FORMULATIONS | Crown Laboratories, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| WO-2021262622-A1 | PROBIOTIC SKIN FORMULATIONS | CROWN LABORATORIES, INC. (US) | 2021-12-30 | — | — | WO | claimed |
| US-20210393510-A1 | PROBIOTIC SKIN FORMULATIONS | HAYFIN SERVICES LLP, AS ADMINISTRATIVE AGENT (GB) | 2021-12-23 | — | — | US | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| US-6583133-B1 | Especially against Gram-positive organisms, e.g. methicillin-sensitive (MSSA) and methicillin- resistant (MRSA) staphylococci, enterococci and pneumococci | BASILEA PHARMACEUTICA AG (CH) | 2003-06-24 | — | — | US | claimed |
| EP-1090013-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067255-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-29 | — | — | WO | claimed |
| US-5057406-A | Aging stability, spectral sensitizers | KONICA CORPORATION (JP) | 1991-10-15 | — | — | US | claimed |
| EP-0341958-A2 | Silver halide photographic material | KONICA CORPORATION (JP) | 1989-11-15 | — | — | EP | claimed |
| US-20250319008-A1 | HAIR COMPOSITIONS USES AND METHODS THEREOF | FUNCTION INC (US) | 2025-10-16 | — | — | US | disclosed |
| WO-2025137404-A1 | ODOR BINDING PROTEIN COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | K18, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-5057406-A | Aging stability, spectral sensitizers | KONICA CORPORATION (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0428112-A1 | Method for processing silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1991-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | PDE4A, PDE4B, PDE3B | MAPK1 1745/4885KDM4E 772/4885HIF1A 2483/4885 |
| US-20250319008-A1 | HAIR COMPOSITIONS USES AND METHODS THEREOF | CUTA, KRT18, NACA | MAPK1 4701/4885KDM4E 801/4885HIF1A 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.