Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402209 | 0.94 | MAPT (0.67) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4397392 | 0.88 | MAPT (0.63) | MAPTLMNAHTTMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5158228 | 0.86 | CLK1 (0.56) | MAPTLMNAHTTMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5157958 | 0.81 | MAPT (0.53) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4394546 | 0.80 | CLK1 (0.56) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL544677 | 0.79 | ABL1 (0.58) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4397032 | 0.79 | CLK1 (0.62) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4398883 | 0.78 | CLK1 (0.53) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4397591 | 0.78 | CLK1 (0.61) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4402171 | 0.78 | ENPP3 (0.56) | MAPTLMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745044-A2 | BENZOTHIAZOLE DERIVATIVES HAVING CDK MODULATING ACTIVITY AND USE THEREOF AS ANTICANCER AGENTS | Aventis Pharma S.A. (FR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005097787-A2 | NOVEL BENZOTHIAZOLES AND THE USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA S.A. (FR) | 2005-10-20 | — | — | WO | disclosed |