Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154886 | 0.89 | — | — | |
| SCHEMBL5158021 | 0.88 | SCN9A (0.31) | — | |
| SCHEMBL5109023 | 0.83 | POLB (0.36) | POLBAPEX1 | |
| SCHEMBL14000735 | 0.82 | IDH1 (0.31) | — | |
| SCHEMBL14000727 | 0.79 | HTT (0.33) | — | |
| SCHEMBL5101875 | 0.78 | MDM2 (0.35) | — | |
| SCHEMBL14561497 | 0.78 | IDH1 (0.31) | — | |
| SCHEMBL5109371 | 0.78 | MAPK1 (0.33) | POLB | |
| SCHEMBL5098995 | 0.77 | MAPT (0.30) | — | |
| SCHEMBL5140205 | 0.75 | RORC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651618-B1 | 2-SUBSTITUTED PYRIMIDINES | BASF AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1651618-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012261-A1 | 2-SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-10 | — | — | WO | disclosed |