Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206590 | 0.85 | MEN1 (0.47) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4072272 | 0.78 | MEN1 (0.84) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL205784 | 0.78 | MEN1 (0.49) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL4055242 | 0.77 | OPRL1 (0.50) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL207488 | 0.76 | MEN1 (0.47) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL4048457 | 0.69 | SMN1; SMN2 (0.41) | ALDH1A1KDM4ETSHRHPGDOPRM1 | |
| SCHEMBL4074980 | 0.68 | MEN1 (0.65) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL4072325 | 0.68 | OPRM1 (0.52) | TSHROPRM1OPRL1LMNA | |
| SCHEMBL12282111 | 0.68 | MEN1 (0.76) | KMT2AMEN1ALDH1A1HSD17B10USP2 | |
| SCHEMBL5572217 | 0.67 | SSTR4 (0.45) | OPRM1OPRL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110974-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |