Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251912 | 0.90 | LTA4H (0.72) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL2027109 | 0.88 | LTA4H (0.69) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL11289347 | 0.83 | LTA4H (0.62) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL6542610 | 0.83 | LTA4H (0.62) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL12869627 | 0.81 | LTA4H (0.60) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL9232175 | 0.81 | LTA4H (0.60) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL28131751 | 0.81 | LTA4H (0.64) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL26949212 | 0.81 | LTA4H (0.64) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL18613819 | 0.80 | LTA4H (0.58) | LTA4HMAOBCYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL7282070 | 0.79 | LTA4H (0.62) | LTA4HMAOBL3MBTL1TDP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751170-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005118603-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-12-15 | — | — | WO | disclosed |