SCHEMBL5158873

SCHEMBL5158873

COC(OC)(OC)OCCO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902247 0.81 CYP4F2 (0.39) TSHRALDH1A1MEN1KMT2A
SCHEMBL892963 0.75 TSHR (0.39) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL22684863 0.74 ALDH1A1 (0.33) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL7760246 0.74
SCHEMBL30712211 0.73 ALDH1A1 (0.32) TSHRALDH1A1
Methoxymethane SCHEMBL2878577 0.71 MAPK1 (0.36) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL5160043 0.70 TSHR (0.54) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL12547206 0.69 TSHR (0.39) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL10987435 0.69 ALDH1A1 (0.45) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL35822 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015075749-A1 NOVEL PROCESSES FOR THE PREPARATION OF VEMURAFENIB LAURUS LABS PRIVATE LIMITED (IN) 2015-05-28 WO claimed
EP-1057852-B1 Polyester film for decorative plate or decorative sheet MITSUBISHI POLYESTER FILM CORP (JP) 2007-02-14 EP disclosed
EP-0839856-B1 Polyester film for decorative plate or decorative sheet MITSUBISHI POLYESTER FILM CORP (JP) 2003-12-17 EP disclosed
EP-1057852-A2 Polyester film for decorative plate or decorative sheet Mitsubishi Polyester Film Corporation (JP) 2000-12-06 EP disclosed
US-6096410-A POLYESTER FILM FOR DECORATIVE PLATE OR HAS OPTICAL DENSITY OF 0.1 TO 5.0, A B VALUE OF NOT LESS THAN-0.5 AND LONGITUDINAL AND TRANSVERSE HEAT SHRINKAGE PERCENTAGES OF NOT LESS THAN -10.0% AND NOT MORE THAN +10.0% AFTER HEAT TREATMENT MITSUBISHI POLYESTER FILM CORPORATION (JP) 2000-08-01 US disclosed
US-5932320-A Polyester film for decorative plate or decorative sheet MITSUBISHI POLYESTER FILM CORPORATION (JP) 1999-08-03 US disclosed
EP-0839856-A2 Polyester film for decorative plate or decorative sheet Mitsubishi Polyester Film Corporation (JP) 1998-05-06 EP disclosed