Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734817 | 0.83 | OPRM1 (0.40) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL20221246 | 0.77 | OPRM1 (0.40) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL17443892 | 0.74 | OPRM1 (0.39) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL2378257 | 0.72 | OPRM1 (0.43) | OPRM1OPRL1SLC6A2OPRK1OPRD1 | |
| SCHEMBL20220987 | 0.71 | CRBN (0.42) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL2379617 | 0.71 | FFAR4 (0.41) | OPRM1OPRL1SLC6A2SLC6A4HSD11B1 | |
| SCHEMBL17443982 | 0.69 | OPRM1 (0.67) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL17443842 | 0.69 | OPRM1 (0.67) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL17443840 | 0.69 | OPRM1 (0.67) | OPRM1OPRL1SLC6A2GRIN1GRIN2A | |
| SCHEMBL19127293 | 0.68 | OPRL1 (0.34) | OPRM1OPRL1SLC6A2GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |