Acetophenone

Acetophenone

SCHEMBL5159246

CC(=O)c1ccccc1.CC(O)c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
LMNA P02545 5/20 0.50
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
HPGD P15428 4/20 0.47
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 2/20 0.46
OPRD1 P41143 1/20 0.45
MAPK1 P28482 2/20 0.45
PTGS1 P23219 2/20 0.44
CXCR1 P25024 2/20 0.44
CXCR2 P25025 2/20 0.44
PTGS2 P35354 2/20 0.44
RECQL P46063 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PMP22 Q01453 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Ethanol SCHEMBL29265545 0.87 LMNA (0.52) LMNACES2CES1HPGDALDH1A1
Phenyl Ethanol SCHEMBL1202059 0.87 LMNA (0.52) LMNACES2CES1HPGDALDH1A1
Acetophenone SCHEMBL28762993 0.87 MAPT (0.60) MAPTSMN1; SMN2LMNACES2CES1
Acetophenone SCHEMBL10608667 0.87 MAPT (0.60) MAPTSMN1; SMN2LMNACES2CES1
Diphenylmethanol SCHEMBL27555686 0.85 SMN1; SMN2 (0.54) MAPTSMN1; SMN2LMNACES2CES1
Acetophenone SCHEMBL11302879 0.85 MAPT (0.54) MAPTSMN1; SMN2LMNACES2CES1
SCHEMBL1262317 0.85 MAPT (0.48) MAPTSMN1; SMN2LMNAHPGDALDH1A1
SCHEMBL17319344 0.85 MAPT (0.48) MAPTSMN1; SMN2LMNAHPGDALDH1A1
Phenyl Ethanol SCHEMBL28552574 0.84 LMNA (0.54) LMNACES2CES1HPGDALDH1A1
Acetophenone SCHEMBL8125316 0.83 SMN1; SMN2 (0.56) MAPTSMN1; SMN2LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1273568-C Process to produce a dilute ethylene stream an a dilute propylene stream CHEVRON PHILLIPS CHEMICAL CO (US) 2006-09-06 CN claimed
CN-113784959-B Chemical recovery method for epoxypropane-styrene monomer process 利安德化学技术有限公司 2023-06-02 CN disclosed
CN-113784959-A Chemical recovery method of epoxypropane-styrene monomer process 利安德化学技术有限公司 2021-12-10 CN disclosed
EP-3890879-A1 HIGHLY ACTIVE AND HIGHLY SELECTIVE COPPER EXTRUDATE CATALYSTS BASF CORPORATION (US) 2021-10-13 EP disclosed
EP-3283468-B1 IMPROVED CATALYST PERFORMANCE IN PROPYLENE EPOXIDATION LYONDELL CHEMICAL TECH LP (US) 2020-09-30 EP disclosed
WO-2020117532-A1 HIGHLY ACTIVE AND HIGHLY SELECTIVE COPPER EXTRUDATE CATALYSTS BASF CORPORATION (US) 2020-06-11 WO disclosed
CN-110368946-A The method that carried non-crystal alloy catalysis hydrogenation of acetophenone prepares alpha-phenyl ethyl alcohol 青岛科技大学 2019-10-25 CN disclosed
CN-108043414-B Hydrogenation of acetophenone prepares the catalyst of alpha-phenyl ethyl alcohol, preparation method and application 万华化学集团股份有限公司 2019-07-30 CN disclosed
CN-109926055-A The method for preparing catalyst of hydrogenation of acetophenone alpha-phenyl ethyl alcohol and application 万华化学集团股份有限公司 2019-06-25 CN disclosed
CN-109926055-A The method for preparing catalyst of hydrogenation of acetophenone alpha-phenyl ethyl alcohol and application 万华化学集团股份有限公司 2019-06-25 CN disclosed
US-4897252-A Production of hydrogen peroxide ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-01-30 US disclosed
US-4897085-A Recovery of hydrogen peroxide ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-01-30 US disclosed
EP-0191208-A1 Production of bis(alpha-alkylbenzyl)ethers ATLANTIC RICHFIELD COMPANY (US) 1986-08-20 EP disclosed
US-4528406-A Production of bis(alpha-alkylbenzyl)ethers ATLANTIC RICHFIELD COMPANY (US) 1985-07-09 US disclosed
US-4521636-A CONDENSATION OF ALPHA ALKYLBENZYL ALCOHOL IN PRESENCE OF ALUMINUM SULFATE CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US disclosed
US-4521637-A ETHERIFICATION OF ALPHA-ALKYLBENZYL ALCOHOL USING ACID TREATED ALUMINA CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US disclosed
US-4521635-A USING ACID-TREATED ALUMINA CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US disclosed
US-4439278-A DINITRO-HYDROXYBENZOIC ACIDS OR ESTERS AS POLYMERIZATION INHIBITORS EASTMAN KODAK COMPANY (US) 1984-03-27 US disclosed
US-4400558-A COMPLEXING WITH METAL HALIDE TO FORM INSOLUBLE ADDUCT ATLANTIC RICHFIELD COMPANY (US) 1983-08-23 US disclosed
US-4389285-A 3,5-DINITROSALICYLIC ACID EASTMAN KODAK COMPANY (US) 1983-06-21 US disclosed