Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637198 | 0.94 | MMP12 (0.52) | MMP12TRPA1TRPV1MMP3MMP8 | |
| SCHEMBL27618004 | 0.94 | MMP12 (0.52) | MMP12TRPA1TRPV1MMP3MMP8 | |
| SCHEMBL27637199 | 0.94 | MMP12 (0.52) | MMP12TRPA1TRPV1MMP3MMP8 | |
| SCHEMBL5575615 | 0.88 | MMP12 (0.55) | MMP12MMP9MMP13MMP2MMP14 | |
| SCHEMBL3810677 | 0.88 | MMP12 (0.55) | MMP12MMP9MMP13MMP2MMP14 | |
| SCHEMBL4611958 | 0.88 | MMP12 (0.55) | MMP12MMP9MMP13MMP2MMP14 | |
| SCHEMBL23117118 | 0.88 | CA1 (0.50) | TRPA1MMP3MMP8MMP9MMP1 | |
| SCHEMBL19032486 | 0.88 | CA1 (0.50) | TRPA1MMP3MMP8MMP9MMP1 | |
| SCHEMBL8608254 | 0.88 | CA1 (0.50) | TRPA1MMP3MMP8MMP9MMP1 | |
| SCHEMBL25238062 | 0.88 | CA1 (0.50) | TRPA1MMP3MMP8MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751126-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | Solvay Pharmaceuticals GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005080366-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-01 | — | — | WO | disclosed |