Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945990 | 0.79 | HTR1A (0.35) | HTR1ADRD2DRD4DRD3ADRA1A | |
| SCHEMBL4945987 | 0.79 | HTR1A (0.37) | HTR1ADRD2DRD4DRD3SLC6A4 | |
| SCHEMBL4947421 | 0.76 | CYP2D6 (0.45) | HTR1ADRD2DRD4DRD3ADRA1A | |
| SCHEMBL4950490 | 0.68 | HTR1A (0.40) | SLC2A1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL4949696 | 0.67 | CYP2D6 (0.45) | HTR1ADRD2DRD4DRD3ADRA1A | |
| SCHEMBL4949793 | 0.66 | SLC2A1 (0.44) | SLC2A1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL4948753 | 0.66 | SLC6A4 (0.42) | SLC2A1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL4945286 | 0.66 | SLC6A2 (0.39) | HTR1ADRD2DRD4DRD3ADRA1A | |
| SCHEMBL4950463 | 0.66 | CYP2D6 (0.40) | HTR1ADRD2DRD4DRD3ADRA1A | |
| SCHEMBL4950991 | 0.65 | HTR1A (0.38) | HTR1ADRD2DRD4DRD3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761524-B1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |
| EP-1761524-A1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006072430-A1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2006-07-13 | — | — | WO | disclosed |