Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160131 | 0.82 | TLR7 (0.54) | TLR7BRD4LMNAMAPTHPGD | |
| SCHEMBL14465845 | 0.80 | TLR7 (0.60) | TLR7BRD4 | |
| SCHEMBL5159469 | 0.79 | TLR7 (0.75) | TLR7 | |
| SCHEMBL10123169 | 0.79 | TLR7 (0.50) | TLR7LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5349914 | 0.77 | TLR7 (0.47) | TLR7LMNAMAPTPDE4APDE4B | |
| SCHEMBL3173290 | 0.77 | TLR7 (0.59) | TLR7LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1897263 | 0.77 | TLR7 (0.58) | TLR7TSHR | |
| SCHEMBL5355630 | 0.77 | MAPT (0.43) | TLR7BRD4LMNAMAPTHPGD | |
| SCHEMBL5617331 | 0.77 | APEX1 (0.49) | TLR7LMNAMAPTPDE4APDE4B | |
| SCHEMBL10123173 | 0.76 | SMN1; SMN2 (0.49) | TLR7BRD4LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765348-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006028545-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |