Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29441981 | 0.94 | — | — | |
| Bicarbonate SCHEMBL31749485 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5163319 | 0.89 | CA4 (0.55) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL5158292 | 0.89 | CA4 (0.42) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL5159853 | 0.89 | CA4 (0.55) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL30932406 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1697622 | 0.88 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1930 | 0.88 | — | — | |
| Bicarbonate SCHEMBL97148 | 0.88 | — | — | |
| Bicarbonate SCHEMBL4929399 | 0.88 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162189-B1 | Process for producing 2-vinylcyclododecanone. | TAKASAGO PERFUMERY CO LTD (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-6548711-B2 | Heating 2-ethylidenecyclododecanone in the presence of a catalyst to establish an isomeration equilibrium state between said Z-isomer, E-isomer and 2- vinylcyclodecanone and separating the 2-vinylcyclododecanone by fractionation | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20020038056-A1 | Process for producing 2-vinylcyclododecanone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-03-28 | — | — | US | disclosed |
| EP-1162189-A2 | Process for producing 2-vinylcyclododecanone. | Takasago International Corporation (JP) | 2001-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038056-A1 | Process for producing 2-vinylcyclododecanone | CYP4A22, CCNY, CYP2J2 | CA4 1785/4885CA1 4157/4885FAHD1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.