Aspartic Acid

Aspartic Acid

SCHEMBL5160188

N[C@@H](CC(=O)O)C(=O)[O-].O.O.[K+]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5

The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
GRM1 Q13255 2/20 0.36
GRM2 Q14416 2/20 0.36
GRM8 O00222 1/20 0.36
GRM6 O15303 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GSR P00390 1/20 0.36
CYP1A2 P05177 1/20 0.36
GRM5 P41594 1/20 0.36
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL27865040 1.00 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL28476128 1.00 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL5195845 1.00 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL50775 0.97 SLC22A6 (0.39) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL888096 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL2828201 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL17350094 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL17747944 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL3976768 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1
Aspartic Acid SCHEMBL20454596 0.95 SLC22A6 (0.38) SLC22A6GABRR1LMNATDP1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4035513-A COSMETICS SHISEIDO CO., LTD. (JA) 1977-07-12 US claimed
US-12383476-B2 W/O/W emulsion composition SHISEIDO COMPANY, LTD. (JP) 2025-08-12 US disclosed
CN-117924105-B Preparation method of potassium aspartate 成都新恒创药业有限公司 2024-05-24 CN disclosed
CN-117924105-A Preparation method of potassium aspartate 成都新恒创药业有限公司 2024-04-26 CN disclosed
US-20220362112-A1 W/O/W EMULSION COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2022-11-17 US disclosed
CN-110015945-B Separation and purification method of sugar alcohol chelated calcium in organic fertilizer 青岛大学 2021-11-09 CN disclosed
WO-2021066098-A1 W/O/W EMULSION COMPOSITION 株式会社 資生堂 2021-04-08 WO disclosed
CN-102408347-A Method for separating and preparing L-aspartic acid chelated potassium dihydrate YIXING QIANCHENG BIOLOG CO LTD 2012-04-11 CN disclosed
CN-102408347-A Method for separating and preparing L-aspartic acid chelated potassium dihydrate YIXING QIANCHENG BIOLOG CO LTD 2012-04-11 CN disclosed
CN-102408347-A Method for separating and preparing L-aspartic acid chelated potassium dihydrate YIXING QIANCHENG BIOLOG CO LTD 2012-04-11 CN disclosed
EP-0781559-B1 Oil adjuvant vaccine and method for preparing same CHEMO SERO THERAPEUT RES INST (JP) 2007-02-07 EP disclosed
US-5814321-A EMULSIFIER NONIONIC SURFACTANTS POLYHYDRIC ALCOHOLS WITH ESTERS, GLYCERIDES AND POLYOXYALKYLENE GLYCOL ESTERS AND ANTIGENS JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE (JP) 1998-09-29 US disclosed
EP-0781559-A2 Oil adjuvant vaccine and method for preparing same Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute (JP) 1997-07-02 EP disclosed
US-4035513-A COSMETICS SHISEIDO CO., LTD. (JA) 1977-07-12 US disclosed