Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344782 | 0.83 | SLC6A4 (0.62) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL27826344 | 0.80 | OPRL1 (0.50) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL517439 | 0.79 | OPRL1 (0.50) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22112097 | 0.79 | OPRM1 (0.49) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4344633 | 0.79 | OPRL1 (0.49) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL316598 | 0.78 | OPRL1 (0.66) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL5572136 | 0.76 | OPRL1 (0.64) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL526471 | 0.76 | OPRM1 (0.52) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3411008 | 0.75 | OPRM1 (0.54) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2202407 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |