Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL516038 | 0.97 | APEX1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL7924264 | 0.96 | APEX1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL54309 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8583231 | 0.96 | APEX1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL516037 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL6236668 | 0.93 | — | — | |
| SCHEMBL22644 | 0.93 | — | — | |
| Fluoride Ion SCHEMBL20213885 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8996402 | 0.89 | — | — | |
| Bromide SCHEMBL3918161 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028855-A1 | SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE | SHRIEVE CHEMICAL PRODUCTS (US) | 2012-02-02 | — | — | US | disclosed |
| US-8022014-B2 | Deep eutectic solvents and applications | SHRIEVE CHEMICAL PRODUCTS, INC. | 2011-09-20 | — | — | US | disclosed |
| US-20110207633-A1 | DEEP EUTECTIC SOLVENTS AND APPLICATIONS | SHRIEVE CHEMICAL PRODUCTS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20090247432-A1 | DEEP EUTECTIC SOLVENTS AND APPLICATIONS | SHRIEVE CHEMICAL PRODUCTS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| WO-2009120839-A2 | DEEP EUTECTIC SOLVENTS AND APPLICATIONS | SHRIEVE CHEMICAL PRODUCTS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |