⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246840 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL16114150 | 0.98 | ANPEP (0.47) | — | |
| Hydrochloric Acid SCHEMBL2439875 | 0.98 | ANPEP (0.47) | — | |
| Hydrochloric Acid SCHEMBL7055449 | 0.89 | UBE2N (0.48) | — | |
| Acetic Acid SCHEMBL5555720 | 0.88 | ANPEP (0.44) | — | |
| Acetic Acid SCHEMBL5555716 | 0.88 | ANPEP (0.44) | — | |
| SCHEMBL2781205 | 0.83 | ANPEP (0.33) | — | |
| SCHEMBL24660875 | 0.81 | PKM (0.35) | — | |
| SCHEMBL12952546 | 0.79 | ANPEP (0.46) | — | |
| SCHEMBL8044785 | 0.79 | TDP1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663228-B | Nuclear magnetic resonance imaging compound, nuclear magnetic resonance imaging agent and application thereof, and nuclear magnetic resonance imaging method | 北京市神经外科研究所 | 2021-01-19 | — | — | CN | disclosed |
| US-10106562-B2 | Process for manufacture of gadofosveset trisodium monohydrate | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-10-23 | — | — | US | disclosed |
| CN-107663228-A | Magnetic resonance imaging compound, magnetic resonance imaging agent and application and magnetic resonance imaging method employing | 北京市神经外科研究所 | 2018-02-06 | — | — | CN | disclosed |
| US-20160016979-A1 | PROCESS FOR MANUFACTURE OF GADOFOSVESET TRISODIUM MONOHYDRATE | CITIZENS BANK, N.A. | 2016-01-21 | — | — | US | disclosed |
| EP-2970140-A1 | PROCESS FOR MANUFACTURE OF GADOFOSVESET TRISODIUM MONOHYDRATE | Lantheus Medical Imaging, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-105209439-A | Process for manufacture of gadofosveset trisodium monohydrate | LANTHEUS MEDICAL IMAGING INC | 2015-12-30 | — | — | CN | disclosed |
| WO-2014160039-A1 | PROCESS FOR MANUFACTURE OF GADOFOSVESET TRISODIUM MONOHYDRATE | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014160039-A1 | PROCESS FOR MANUFACTURE OF GADOFOSVESET TRISODIUM MONOHYDRATE | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-7927581-B2 | For magnetic resonance imaging (MRI); peptide modified at its N- and its C-termini, independently, with a moiety comprising a metal chelate complex; specific binding affinity for fibrin; sufficient half-life in vivo | Factor 1A, LLC (US) | 2011-04-19 | — | — | US | disclosed |
| US-7238341-B2 | Peptide-based multimeric targeted contrast agents | EPIX PHARMACEUTICALS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7189879-B2 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | SCHERING AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7189879-B2 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | SCHERING AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7189879-B2 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | SCHERING AG (DE) | 2007-03-13 | — | — | US | disclosed |
| EP-1748977-A1 | METHOD FOR PRODUCING 1-HYDROXYMETHYL-1,3,5-TRIAZAPENTANE, TRIHYDROCHLORIDE | Schering Aktiengesellschaft (DE) | 2007-02-07 | — | — | EP | disclosed |
| US-20060039861-A1 | Peptide-based multimeric targeted contrast agents | EPIX MEDICAL, INC., A DELAWARE CORPORATION | 2006-02-23 | — | — | US | disclosed |
| US-20060014983-A1 | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-01-19 | — | — | US | disclosed |
| WO-2005115968-A1 | METHOD FOR PRODUCING 1-HYDROXYMETHYL-1,3,5-TRIAZAPENTANE, TRIHYDROCHLORIDE | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | WO | disclosed |
| US-20050074411-A1 | Peptide-based multimeric targeted contrast agents | EPIX MEDICAL, INC. A DELAWARE CORPORATION | 2005-04-07 | — | — | US | disclosed |