SCHEMBL516047

SCHEMBL516047

OCCNC1CCC(O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.41
SPHK1 Q9NYA1 1/20 0.38
KDM4E B2RXH2 1/20 0.36
KDM1A O60341 2/20 0.36
LMNA P02545 1/20 0.35
GBA1 P04062 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CNR1 P21554 1/20 0.35
TBXA2R P21731 1/20 0.35
HRH2 P25021 1/20 0.35
SLC6A4 P31645 1/20 0.35
KCNH2 Q12809 1/20 0.35
HIF1A Q16665 1/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DPP4 P27487 1/20 0.33
AXL P30530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16002007 1.00 EPHX2 (0.41) EPHX2SPHK1KDM4EKDM1ALMNA
SCHEMBL701060 0.89
SCHEMBL18045582 0.89 SPHK1 (0.42) SPHK1KDM4EKDM1ADPP4
Bromide SCHEMBL2833578 0.87
SCHEMBL1796153 0.86 KDM4E (0.40) EPHX2SPHK1KDM4ELMNAGBA1
SCHEMBL1484842 0.79
SCHEMBL3429410 0.79
SCHEMBL24429571 0.78 ALDH1A1 (0.41) SPHK1KDM4EKDM1ATSHR
SCHEMBL1795636 0.78 EPHX2 (0.39) EPHX2KDM4ELMNAGBA1CYP1A2
SCHEMBL24429564 0.78 ALDH1A1 (0.41) SPHK1KDM4EKDM1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029448-B2 Method for preparing aqueous suspensions of mineral materials using amines in combination with vinyl-carboxylic polymers OMYA INTERNATIONAL AG (CH) 2015-05-12 US claimed
US-8545617-B2 Neutralizing and co-dispersion agent with strong capacity for developing coloring power, and paints and pigment concentrates containing same ARKEMA FRANCE (FR) 2013-10-01 US claimed
EP-2640786-A1 METHOD FOR PREPARING AQUEOUS SUSPENSIONS OF MINERAL MATERIALS USING AMINES IN COMBINATION WITH VINYL CARBOXYLIC POLYMERS Omya Development AG (CH) 2013-09-25 EP claimed
EP-2455429-B1 Method for preparing aqueous suspensions of mineral materials using amines combined with vinyl carboxylic polymers OMYA DEVELOPMENT AG (CH) 2013-08-14 EP claimed
US-20120129986-A1 USE OF AMINES IN COMBINATION WITH ACRYLIC POLYMERS IN THE MANUFACTURE OF AQUEOUS SUSPENSIONS OF MINERAL MATTERS COATEX S.A.S. (FR) 2012-05-24 US claimed
WO-2012066410-A1 METHOD FOR PREPARING AQUEOUS SUSPENSIONS OF MINERAL MATERIALS USING AMINES IN COMBINATION WITH VINYL CARBOXYLIC POLYMERS OMYA DEVELOPMENT AG (CH) 2012-05-24 WO claimed
EP-2455429-A1 Method for preparing aqueous suspensions of mineral materials using amines combined with vinyl carboxylic polymers Omya Development AG (CH) 2012-05-23 EP claimed
US-20120024193-A1 NEUTRALIZING AND CO-DISPERSION AGENT WITH STRONG CAPACITY FOR DEVELOPING COLORING POWER, AND PAINTS AND PIGMENT CONCENTRATES CONTAINING SAME ARKEMA FRANCE (FR) 2012-02-02 US claimed
EP-2227316-A2 NEUTRALISATION AND CO-DISPERSION AGENT HAVING A HIGH COLOURING-POWER ENHANCEMENT CAPACITY, AND PAINTS AND PIGMENT CONCENTRATES CONTAINING SAME ARKEMA FRANCE (FR) 2010-09-15 EP claimed
WO-2009087330-A2 NEUTRALISATION AND CO-DISPERSION AGENT HAVING A HIGH COLOURING-POWER ENHANCEMENT CAPACITY, AND PAINTS AND PIGMENT CONCENTRATES CONTAINING SAME ARKEMA FRANCE (FR) 2009-07-16 WO claimed
US-20230286902-A1 LIPID NANOPARTICLE COMPOSITION Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-09-14 US disclosed
WO-2023098842-A1 NUCLEIC ACID VACCINES FOR CORONAVIRUS BASED ON SEQUENCES DERIVED FROM SARS-CoV-2 OMICRON STRAIN Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-06-08 WO disclosed
WO-2023056911-A1 MULTIVALENT NUCLEIC ACID VACCINES FOR CORONAVIRUS BASED ON SEQUENCES DERIVED FROM SARS-CoV-2 BETA AND DELTA STRAINS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-04-13 WO disclosed
US-11472766-B2 Lipid nanoparticle composition Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-10-18 US disclosed
US-20220153686-A1 LIPID NANOPARTICLE COMPOSITION Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-05-19 US disclosed
US-20060270692-A1 Chemical compounds ASTRAZENECA AB (SE) 2006-11-30 US disclosed
EP-1613619-A1 QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER AstraZeneca AB (SE) 2006-01-11 EP disclosed
WO-2004094410-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2004-11-04 WO disclosed
US-6004669-A ELECTROSTATIC CHARGING MEMBER, UNIFORMLY DISPERSED IN A MODIFIED RESIN AS A BASE POLYMER BEING MODIFIED BY AN AMINE GROUP WHICH HAS AN ACID-BASE INTERACTION WITH THE OXIDATION-PROCESSED ELECTRICALLY-CONDUCTING AGENT, FUJI XEROX CO., LTD. (JP) 1999-12-21 US disclosed
US-4211699-A FROM A DIISOCYANATE, AN AMINO- OR HYDRAZINO DIOL, AND A MASKING LACTAM BAYER AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286902-A1 LIPID NANOPARTICLE COMPOSITION CETP, NPC1, LCAT EPHX2 2487/4885SPHK1 1219/4885KDM4E 4495/4885
US-20220153686-A1 LIPID NANOPARTICLE COMPOSITION CETP, NPC1, LCAT EPHX2 2487/4885SPHK1 1219/4885KDM4E 4495/4885
US-11472766-B2 Lipid nanoparticle composition CETP, NPC1, LCAT EPHX2 2487/4885SPHK1 1219/4885KDM4E 4495/4885
US-20060270692-A1 Chemical compounds CCNI, MKI67, TP53 EPHX2 3994/4885SPHK1 2758/4885KDM4E 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.