SCHEMBL5160529

SCHEMBL5160529

COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634991 1.00 GHSR (1.00) GHSR
SCHEMBL3634996 1.00 GHSR (1.00) GHSR
SCHEMBL3674829 0.95 GHSR (1.00) GHSR
SCHEMBL3637144 0.95 GHSR (1.00) GHSR
SCHEMBL3637142 0.95 GHSR (1.00) GHSR
SCHEMBL3679140 0.95 GHSR (1.00) GHSR
SCHEMBL3679139 0.95 GHSR (1.00) GHSR
SCHEMBL3674831 0.95 GHSR (1.00) GHSR
SCHEMBL3679545 0.95 GHSR (1.00) GHSR
SCHEMBL4113402 0.94 GHSR (0.89) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757290-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors Zentaris GmbH (DE) 2007-02-28 — — EP claimed
EP-1757290-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors Zentaris GmbH (DE) 2007-02-28 — — EP disclosed
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