Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylic Acid SCHEMBL6434928 | 0.75 | CYP2C9 (0.55) | CYP2C9KEAP1NFE2L2 | |
| SCHEMBL17294705 | 0.75 | ATM (0.50) | — | |
| SCHEMBL30128750 | 0.75 | ATM (0.50) | — | |
| SCHEMBL17300855 | 0.75 | HTR2C (0.45) | HTR6 | |
| SCHEMBL15935173 | 0.75 | HTR2C (0.45) | HTR6 | |
| SCHEMBL17300856 | 0.75 | HTR2C (0.45) | HTR6 | |
| SCHEMBL16455234 | 0.75 | HTR2C (0.66) | HTR6 | |
| Benzylic Acid SCHEMBL27825208 | 0.74 | CYP2C9 (0.53) | CYP2C9KEAP1NFE2L2 | |
| SCHEMBL1004280 | 0.74 | CHRM3 (0.54) | HTR6CYP2C9 | |
| Hydrochloric Acid SCHEMBL16446229 | 0.74 | HTR2C (0.67) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11152270-A | — | — | None | — | — | JP | disclosed |
| EP-1275645-B1 | LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM | HAMAMATSU PHOTONICS KK (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1275645-A1 | LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM | HAMAMATSU PHOTONICS K. K. (JP) | 2003-01-15 | — | — | EP | disclosed |
| JP-H11152270-A | MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM LABELED COMPOUND AND ITS SYNTHESIS | HAMAMATSU PHOTONICS KK | 1999-06-08 | — | — | JP | disclosed |