Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991003 | 0.90 | OPRM1 (0.50) | OPRM1OPRL1MEN1KMT2ALMNA | |
| SCHEMBL2974572 | 0.88 | OPRM1 (0.64) | OPRM1OPRL1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2976610 | 0.87 | OPRM1 (0.66) | OPRM1OPRL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL210046 | 0.84 | OPRM1 (0.46) | OPRM1OPRL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4074077 | 0.82 | OPRM1 (0.51) | OPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL4074080 | 0.81 | OPRM1 (0.51) | OPRM1OPRL1 | |
| SCHEMBL4079677 | 0.78 | OPRM1 (0.47) | OPRM1OPRL1 | |
| 3-Phenoxyaniline SCHEMBL248578 | 0.78 | OPRM1 (0.44) | OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL206971 | 0.77 | MAPT (0.49) | OPRM1OPRL1MEN1KMT2APOLB | |
| SCHEMBL205762 | 0.76 | OPRM1 (0.46) | OPRM1OPRL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747191-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION | Grünenthal GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005110975-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |