SCHEMBL5161287

SCHEMBL5161287

OCCOc1cccc2ccccc12.[Na]

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 11/20 0.68
HTR1D P28221 3/20 0.68
KCNA3 P22001 1/20 0.61
IDO1 P14902 1/20 0.58
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
SLC6A4 P31645 2/20 0.57
HRH1 P35367 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
HPGD P15428 2/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023529 0.98 HTR1B (0.70) HTR1BHTR1DKCNA3IDO1KDM4E
SCHEMBL5161278 0.96 HTR1B (0.68) HTR1BHTR1DKCNA3IDO1KDM4E
SCHEMBL3607496 0.89 HTR1B (0.68) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL28852559 0.87 HTR1B (0.58) HTR1BHTR1DKCNA3IDO1KDM4E
SCHEMBL16021963 0.87 KDM4E (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL16021983 0.87 KDM4E (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL16021973 0.87 KDM4E (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL8091013 0.87 KDM4E (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL16021969 0.87 KDM4E (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1
SCHEMBL6272756 0.87 KCNA3 (0.69) HTR1BHTR1DKCNA3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403042-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-03-14 EP disclosed
US-7081329-B2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-07-25 US disclosed
EP-1195646-B1 Photosensitive lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-02-09 EP disclosed
US-6777155-B2 PHOTOSENSITIVE LAYER INCLUDES A POLYURETHANE RESIN BINDER COMPRISING AN ALIPHATIC CYCLIC STRUCTURE WHICH HAS A CARBOXYL GROUP AS A SUBSTITUENT FUJI PHOTO FILM CO., LTD. (JP) 2004-08-17 US disclosed
EP-1403042-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-03-31 EP disclosed
EP-1195646-A1 Photosensitive lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-04-10 EP disclosed