Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.68 |
| ▸ | HTR1D | P28221 | 2/20 | 0.68 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.66 |
| ▸ | CNR2 | P34972 | 3/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28443504 | 0.98 | HTR1B (0.66) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL6272756 | 0.94 | KCNA3 (0.69) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL1007097 | 0.93 | KCNA3 (0.67) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL8955863 | 0.93 | KCNA3 (0.67) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL4647042 | 0.93 | KCNA3 (0.67) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL6438840 | 0.93 | KCNA3 (0.67) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL8544058 | 0.93 | KCNA3 (0.67) | HTR1BHTR1DKCNA3CNR2CNR1 | |
| SCHEMBL1023529 | 0.90 | HTR1B (0.70) | HTR1BHTR1DKCNA3SLC6A4HRH1 | |
| SCHEMBL5161287 | 0.89 | HTR1B (0.68) | HTR1BHTR1DKCNA3SLC6A4HRH1 | |
| SCHEMBL5161278 | 0.89 | HTR1B (0.68) | HTR1BHTR1DKCNA3SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633549-B2 | Ink, ink accommodating container, image forming method, and image forming device | RICOH COMPANY, LTD. (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20190264050-A1 | INK, INK ACCOMMODATING CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING DEVICE | RICOH COMPANY, LTD. (JP) | 2019-08-29 | — | — | US | disclosed |
| CN-103608337-B | 18F-labeled precursor of PET radioactive medical supplies and preparation method thereof | FUTURECHEM株式会社 | 2016-07-06 | — | — | CN | disclosed |
| CN-105732309-A | Chiral preparation method of dapoxetine hydrochloride key intermediate | 山东省药学科学院 | 2016-07-06 | — | — | CN | disclosed |
| US-20150344733-A1 | RESIN COMPOSITION, PREPREG, LAMINATE, METAL FOIL-CLAD LAMINATE, AND PRINTED-WIRING BOARD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-12-03 | — | — | US | disclosed |
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2010-03-25 | — | — | US | disclosed |
| EP-2089395-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UnibioScreen S.A. (BE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008043846-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2008-04-17 | — | — | WO | disclosed |
| EP-0126397-B1 | NAPHTHALENE DERIVATIVE, POLYMERIZABLE COMPOSITION CONTAINING THE SAME AND POLYMER OBTAINABLE BY POLYMERIZING THIS COMPOSITION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0102034-B1 | SPIRO(2H-1,4-BENZODIOXEPIN-3(5H)4'-PIPERIDINE AND 3'-PYRROLIDINO) COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4521537-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-04 | — | — | US | disclosed |
| EP-0126397-A2 | Naphthalene derivative, polymerizable composition containing the same and polymer obtainable by polymerizing this composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1984-11-28 | — | — | EP | disclosed |
| EP-0102034-A1 | Spiro(2H-1,4-benzodioxepin-3(5H)4'-piperidine and 3'-pyrrolidino) compounds, a process for preparing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4376125-A | Aminobenzlpropranolol and pharmaceutical preparation thereof | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | MIF, IMPDH1, IMPDH2 | HTR1B 3401/4885HTR1D 3783/4885KCNA3 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.