Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815598 | 0.94 | MEN1 (0.61) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL27815600 | 0.94 | MEN1 (0.61) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL5709937 | 0.94 | MEN1 (0.61) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL5709848 | 0.94 | MEN1 (0.61) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL5158545 | 0.90 | MEN1 (0.68) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL27340330 | 0.87 | TSHR (0.53) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL28485015 | 0.85 | TSHR (0.51) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL8168380 | 0.85 | KCNN4 (0.55) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL28558105 | 0.85 | TSHR (0.54) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL7357017 | 0.84 | TSHR (0.50) | MEN1KMT2APOLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275645-B1 | LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM | HAMAMATSU PHOTONICS KK (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-6649142-B2 | Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system | HAMAMATSU PHOTONICS K.K. (JP) | 2003-11-18 | — | — | US | disclosed |
| US-20030113261-A1 | Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system | HAMAMATSU PHOTONICS K.K. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1275645-A1 | LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM | HAMAMATSU PHOTONICS K. K. (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113261-A1 | Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system | CHRM3, CHRM5, CHRM2 | MEN1 666/4885KMT2A 2694/4885POLB 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.