Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28137293 | 0.86 | TSHR (0.51) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL5161453 | 0.84 | MEN1 (0.64) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL27340330 | 0.84 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL6893556 | 0.83 | TSHR (0.49) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28485015 | 0.83 | TSHR (0.51) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL8168380 | 0.82 | KCNN4 (0.55) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28558105 | 0.82 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL27902505 | 0.81 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL2418304 | 0.81 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL14258113 | 0.81 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |