SCHEMBL5161849

SCHEMBL5161849

CCCC[SnH].O=C(O)C(O)C(O)C(O)C(O)C(O)C(O)CO.O=C(O)C(O)C(O)C(O)C(O)C(O)C(O)CO.O=C(O)C(O)C(O)C(O)C(O)C(O)C(O)CO

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.63
LMNA P02545 2/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
KDM4E B2RXH2 2/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL28152796 0.88 PDE4A (0.76) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL29564356 0.88 PDE4A (0.76) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL27700133 0.84 PDE4A (0.70) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL5338817 0.84 PDE4A (0.70) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL29034483 0.82 PDE4A (0.86) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL28168949 0.82 PDE4A (0.86) PDE4ALMNAUSP2SLCO1B1TDP1
Methyl Alcohol SCHEMBL10603144 0.82 PDE4A (0.86) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL30529944 0.82 PDE4A (0.86) PDE4ALMNAUSP2SLCO1B1TDP1
Gluconic Acid SCHEMBL31354688 0.82 PDE4A (0.86) PDE4ALMNAUSP2SLCO1B1TDP1
SCHEMBL3761726 0.82 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323785-B1 Radiation curable powder lacquer compositions and their use DEGUSSA (DE) 2007-02-28 EP disclosed
EP-1323758-B1 Radiation curable powder lacquer compositions and their use DEGUSSA (DE) 2006-04-12 EP disclosed
EP-1520890-B1 Powder coating compositions based on urethane(meth)acrylates and micronise waxs and their use DEGUSSA (DE) 2005-11-30 EP disclosed
EP-1520890-A1 Powder coating compositions based on urethane(meth)acrylates and micronise waxs and their use Degussa AG (DE) 2005-04-06 EP disclosed
EP-1496084-A1 Radiation curable powder lacquer compositions and their use Degussa AG (DE) 2005-01-12 EP disclosed
EP-1323758-A2 Radiation curable powder lacquer compositions and their use Degussa AG (DE) 2003-07-02 EP disclosed
EP-1323785-A2 Radiation curable powder lacquer compositions and their use Degussa AG (DE) 2003-07-02 EP disclosed