Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570918 | 0.99 | ALDH1A1 (0.58) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2009359 | 0.85 | ALDH1A1 (0.73) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2008427 | 0.84 | ALDH1A1 (0.76) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2005591 | 0.80 | ALDH1A1 (0.64) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL2011664 | 0.80 | GRIA4 (0.54) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2011337 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2013461 | 0.79 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2AHDAC4 | |
| SCHEMBL2004233 | 0.79 | ALDH1A1 (0.67) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL2009617 | 0.79 | ALDH1A1 (0.67) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL12570922 | 0.79 | CA12 (0.63) | ALDH1A1PKMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756046-A2 | ARYL ALKYL SULFONAMIDES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE CONDITIONS | The University Court of The University of Aberdeen (GB) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118528-A2 | ARYL ALKYL SULFONAMIDES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE CONDITIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2005-12-15 | — | — | WO | disclosed |