Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.80 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL13560601 | 1.00 | — | — | |
| Nitric Acid SCHEMBL5821023 | 0.95 | — | — | |
| Nitric Acid SCHEMBL28411161 | 0.89 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL3762342 | 0.89 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL10981408 | 0.89 | — | — | |
| Nitric Acid SCHEMBL7750558 | 0.89 | — | — | |
| Nitric Acid SCHEMBL302522 | 0.89 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL234 | 0.89 | — | — | |
| Nitric Acid SCHEMBL37356 | 0.89 | — | — | |
| Nitric Acid SCHEMBL8383283 | 0.89 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755778-A1 | CATALYSTS FOR THE SIMULTANEOUS REMOVAL OF CARBON MONOXIDE AND HYDROCARBONS FROM OXYGEN-RICH EXHAUST GASES AND PROCESSES FOR THE MANUFACTURE THEREOF | HTE Aktiengesellschaft The High Throughput Experimentation Company (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005102513-A1 | CATALYSTS FOR THE SIMULTANEOUS REMOVAL OF CARBON MONOXIDE AND HYDROCARBONS FROM OXYGEN-RICH EXHAUST GASES AND PROCESSES FOR THE MANUFACTURE THEREOF | HTE AKTIENGESELLSCHAFT THE HIGH THROUGHPUT EXPERIMENTATION COMPANY (DE) | 2005-11-03 | — | — | WO | disclosed |