Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555751 | 0.92 | MEN1 (0.53) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3556914 | 0.91 | WDR5 (0.52) | MEN1KMT2ALMNAHTTLIMK2 | |
| SCHEMBL3559245 | 0.85 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3563411 | 0.84 | AR (0.54) | MEN1KMT2ALMNAHTTLIMK2 | |
| SCHEMBL3555874 | 0.83 | CA12 (0.56) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3552400 | 0.82 | AR (0.60) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL3558099 | 0.82 | FABP1 (0.54) | MEN1KMT2ALMNAHTTPKM | |
| SCHEMBL3560475 | 0.81 | HDAC1 (0.55) | MEN1KMT2ALMNALIMK2PKM | |
| SCHEMBL3562939 | 0.81 | AR (0.58) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL3553481 | 0.81 | AR (0.58) | MEN1KMT2ALMNAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |