SCHEMBL516220

SCHEMBL516220

COC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.38
KMT2A Q03164 2/20 0.38
CA14 Q9ULX7 2/20 0.36
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
CA12 O43570 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LTA4H P09960 1/20 0.33
MME P08473 1/20 0.32
PGD P52209 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13601621 1.00 TSHR (0.56) TSHRSMN1; SMN2TP53KMT2ACA14
SCHEMBL10295990 1.00 TSHR (0.56) TSHRSMN1; SMN2TP53KMT2ACA14
SCHEMBL29051545 0.97 TSHR (0.53) TSHRSMN1; SMN2TP53KMT2ACA14
Ammonia Solution, Strong SCHEMBL21219106 0.97 TSHR (0.53) TSHRSMN1; SMN2TP53KMT2ACA14
Butanedione SCHEMBL11722429 0.93 TSHR (0.48) TSHRSMN1; SMN2TP53KMT2ACA14
Water SCHEMBL28077825 0.93 TSHR (0.48) TSHRSMN1; SMN2TP53KMT2ACA14
SCHEMBL590895 0.88 SMN1; SMN2 (0.50) TSHRSMN1; SMN2KMT2ACA14CA12
SCHEMBL13266324 0.88 SMN1; SMN2 (0.50) TSHRSMN1; SMN2KMT2ACA14CA12
SCHEMBL6064611 0.88 SMN1; SMN2 (0.50) TSHRSMN1; SMN2KMT2ACA14CA12
SCHEMBL590894 0.88 SMN1; SMN2 (0.50) TSHRSMN1; SMN2KMT2ACA14CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724307-B1 LAUNDRY SURFACTANTS HAVING INHERENT BUILDING CAPACITY DERIVED FROM BIO-BASED HYDROYACIDS AND EPOXIDES; AND PROCESS THEREFORE BATTELLE MEMORIAL INSTITUTE (US) 2025-07-16 EP claimed
WO-2024077407-A1 CHIRAL REDUCING AGENT AND METHOD FOR SYNTHESIZING CHIRAL NICOTINE 成都化润药业有限公司 2024-04-18 WO claimed
CN-117480174-A Chiral reducing agent and method for synthesizing chiral nicotine 成都化润药业有限公司 2024-01-30 CN claimed
US-11872234-B2 Vareniciline compound and process of manufacture thereof PAR PHARMACEUTICAL, INC. (US) 2024-01-16 US claimed
CN-117064626-A Medical hydrogel patch 浙江银达生物技术有限公司 2023-11-17 CN claimed
CN-116849913-A Manufacturing method of medical hydrogel patch 浙江银达生物技术有限公司 2023-10-10 CN claimed
US-11779587-B2 Vareniciline compound and process of manufacture thereof PAR PHARMACEUTICAL, INC. (US) 2023-10-10 US claimed
US-20230285406-A1 VARENICILINE COMPOUND AND PROCESS OF MANUFACTURE THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2023-09-14 US claimed
US-20230285407-A1 VARENICILINE COMPOUND AND PROCESS OF MANUFACTURE THEREOF WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2023-09-14 US claimed
US-20220275314-A1 GLYCEROL BASED DETERGENT BUILDERS AND ADDITIVES BATTELLE MEMORIAL INSTITUTE 2022-09-01 US claimed
EP-1536291-A1 REMOVING SOLUTION Daikin Industries, Ltd. (JP) 2005-06-01 EP claimed
US-20050016733-A1 Well treatment fluid compositions and methods for their use COMBINED SYSTEMS, INC. 2005-01-27 US claimed
US-20020125012-A1 Well treatment fluid compositions and methods for their use BJ SERVICES COMPANY 2002-09-12 US claimed
WO-2002055843-A1 WELL TREATMENT FLUID COMPOSITIONS AND METHODS FOR THEIR USE BJ SERVICES COMPANY (US) 2002-07-18 WO claimed
CN-1203224-A Process for preparation of (1S,2R)-1-amino-2-indanol-(R,R)-tartrate methanol solvate DSM NV (NL) 1998-12-30 CN claimed
EP-0540654-B1 LOW FRICTION SEAL ASSEMBLY MATHER SEAL CO (US) 1995-01-11 EP claimed
EP-0540654-A1 LOW FRICTION SEAL ASSEMBLY. MATHER SEAL CO (US) 1993-05-12 EP claimed
WO-1992001881-A1 LOW FRICTION SEAL ASSEMBLY MATHER SEAL COMPANY (US) 1992-02-06 WO claimed
US-5015001-A Low friction seal assembly MATHER SEAL COMPANY (US) 1991-05-14 US claimed
US-4059463-A Process for producing ferromagnetic powder FUJI PHOTO FILM CO., LTD. (JA) 1977-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285407-A1 VARENICILINE COMPOUND AND PROCESS OF MANUFACTURE THEREOF COMT, CYP2C9, CYP3A7 TSHR 3315/4885SMN1; SMN2 1547/4885TP53 4755/4885
US-11779587-B2 Vareniciline compound and process of manufacture thereof COMT, CYP2C9, CYP3A7 TSHR 3315/4885SMN1; SMN2 1547/4885TP53 4755/4885
US-11872234-B2 Vareniciline compound and process of manufacture thereof COMT, CYP2C9, CYP3A7 TSHR 3315/4885SMN1; SMN2 1547/4885TP53 4755/4885
US-20230285406-A1 VARENICILINE COMPOUND AND PROCESS OF MANUFACTURE THEREOF COMT, CYP2C9, CYP3A7 TSHR 3315/4885SMN1; SMN2 1547/4885TP53 4755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.