Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 13/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133586 | 1.00 | NOD1 (0.61) | NOD1SLC6A5HAO1PLA2G2APLA2G5 | |
| SCHEMBL1712903 | 1.00 | NOD1 (0.61) | NOD1SLC6A5HAO1PLA2G2APLA2G5 | |
| SCHEMBL1449056 | 0.98 | NOD1 (0.59) | NOD1SLC6A5HAO1PLA2G2APLA2G5 | |
| SCHEMBL1449055 | 0.98 | NOD1 (0.59) | NOD1SLC6A5HAO1PLA2G2APLA2G5 | |
| Lactic Acid SCHEMBL28953041 | 0.94 | NOD1 (0.56) | NOD1SLC6A5HAO1PLA2G2APLA2G5 | |
| SCHEMBL22996019 | 0.89 | NOD1 (0.77) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL5122358 | 0.89 | NOD1 (0.77) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL17941648 | 0.89 | NOD1 (0.77) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL9829330 | 0.89 | NOD1 (0.77) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL131586 | 0.89 | NOD1 (0.77) | NOD1SLC6A5FAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190221281-A1 | METHODS AND SYSTEMS FOR QUANTIFYING GENE EXPRESSION IN SYNTHETIC GENE CIRCUITS AND FOR TUNING SYNTHETIC GENE CIRUITS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-18 | — | — | US | disclosed |
| EP-1470221-B1 | RALSTONIA AHL-ACYLASE GENE | AGENCY SCIENCE TECH & RES (SG) | 2007-03-21 | — | — | EP | disclosed |
| US-7098014-B2 | Ralstonia ahl-acylase gene | ZHANG LIAN HUI | 2006-08-29 | — | — | US | disclosed |
| US-20050155088-A1 | Ralstonia ahl-acylase gene | ZHANG LIAN H (SG) | 2005-07-14 | — | — | US | disclosed |
| EP-1470221-A1 | RALSTONIA AHL-ACYLASE GENE | Agency for Science, Technology and Research (SG) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003068951-A1 | RALSTONIA AHL-ACYLASE GENE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2003-08-21 | — | — | WO | disclosed |