SCHEMBL5162573

SCHEMBL5162573

C=C(C(=O)OCCCCCC)C(C)C=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
KDM4E B2RXH2 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
EGFR P00533 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PPARG P37231 3/20 0.41
BCHE P06276 2/20 0.40
APP P05067 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3400829 0.85 SMN1; SMN2 (0.43) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL8675032 0.84 KDM4E (0.43) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL11317319 0.83 KDM4E (0.43) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL668688 0.81 TSHR (0.52) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL10901969 0.81 TSHR (0.52) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL7457989 0.81 TSHR (0.52) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL9172160 0.81 KDM4E (0.47) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL8677173 0.79 KDM4E (0.47) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL9442161 0.79 TSHR (0.47) TSHRALDH1A1LMNAKDM4ETDP1
SCHEMBL7242327 0.79 TSHR (0.47) TSHRALDH1A1LMNAKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998002197-A1 THROMBORESISTANT COATING MADE OF ACRYLIC POLYMER COOPER ROBIN PETER (GB) 1998-01-22 WO claimed
CN-101424890-B External additive, method of manufacturing same and toner RICOH CO LTD 2012-01-04 CN disclosed
CN-201716522-U Black carbon powder JIANG LIU 2011-01-19 CN disclosed
EP-1434844-B1 CLEANING WIPE UNILEVER PLC (GB) 2007-03-07 EP disclosed
EP-1343867-B1 ANTIMICROBIAL WIPE UNILEVER PLC (GB) 2006-10-11 EP disclosed
EP-1434844-A2 CLEANING WIPE UNILEVER PLC (GB) 2004-07-07 EP disclosed
EP-1348016-A1 ANTIMICROBIAL CLEANING COMPOSITIONS UNILEVER PLC (GB) 2003-10-01 EP disclosed
EP-1343867-A2 ANTIMICROBIAL WIPE UNILEVER PLC (GB) 2003-09-17 EP disclosed
WO-2002092750-A1 ANTIMICROBIAL CLEANING WIPE UNILEVER PLC (GB) 2002-11-21 WO disclosed
WO-2002090483-A2 CLEANING WIPE UNILEVER PLC (GB) 2002-11-14 WO disclosed
WO-2002090484-A2 HARD SURFACE CLEANING WIPE UNILEVER PLC (GB) 2002-11-14 WO disclosed
WO-2002050225-A1 ANTIMICROBIAL CLEANING COMPOSITIONS UNILEVER PLC (GB) 2002-06-27 WO disclosed
WO-2002050241-A2 ANTIMICROBIAL WIPE UNILEVER PLC (GB) 2002-06-27 WO disclosed
WO-1998002197-A1 THROMBORESISTANT COATING MADE OF ACRYLIC POLYMER COOPER ROBIN PETER (GB) 1998-01-22 WO disclosed
US-5229441-A Maltenes and asphaltene AMERICAN GILSONITE COMPANY (US) 1993-07-20 US disclosed
US-5190997-A Protective colloid of crosslinked polymer in aqueous emulsions SEQUA CHEMICALS, INC. (US) 1993-03-02 US disclosed
US-4437271-A Surface treating pad having a renewable surface MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-03-20 US disclosed