Deoxyuridine Monophosphate

SCHEMBL5162672

O=c1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=c1ccn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.71

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	13/20	0.71

▸	P2RY6	Q15077	8/20	0.71

▸	P2RY4	P51582	8/20	0.71

▸	P2RY14	Q15391	5/20	0.67

▸	DUT	P33316	1/20	0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Uridine_Diphosphate SCHEMBL28961444	0.93	P2RY6 (0.77)	P2RY2P2RY6P2RY4P2RY14
Deoxyuridine Monophosphate SCHEMBL8200	0.92	DUT (0.77)	DUT
Deoxyuridine Monophosphate SCHEMBL25024676	0.92	DUT (0.77)	DUT
Deoxyuridine Monophosphate SCHEMBL21941035	0.92	DUT (0.77)	DUT
Deoxyuridine Monophosphate SCHEMBL888328	0.92	DUT (0.77)	DUT
SCHEMBL4071893	0.91	P2RY6 (0.83)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL2683846	0.91	P2RY6 (0.83)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL2056922	0.91	P2RY6 (0.83)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL157644	0.91	P2RY6 (0.83)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL157645	0.91	P2RY6 (0.83)	P2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1758915-A2	COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION	Inspire Pharmaceuticals, Inc. (US)	2007-03-07	—	—	EP	disclosed
WO-2005097814-A2	COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION	INSPIRE PHARMACEUTICALS, INC. (US)	2005-10-20	—	—	WO	disclosed