Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 0.47 |
| ▸ | RARG | P13631 | 16/20 | 0.47 |
| ▸ | RARA | P10276 | 15/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506863 | 0.90 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4497627 | 0.90 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6247945 | 0.84 | RARB (0.47) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6253766 | 0.83 | RARB (0.49) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4492045 | 0.82 | RARB (0.50) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6250578 | 0.79 | RARA (0.41) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4500556 | 0.76 | RARB (0.46) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4500557 | 0.76 | RARB (0.46) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4512288 | 0.75 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4512285 | 0.75 | RARB (0.48) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565433-B1 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2007-03-14 | — | — | EP | disclosed |